Screening of Kunun-zaki for the Presence of Extended Spectrum Beta Lactamase (ESBL) and Carbapenemase Producing Escherichia Coli

Kelechi Chikanma Edward, Chukwuemeka Eric Alozie, Precious Obioha Owuamalam, Onyedikachi Victor Onyekachi

© 2019 Kelechi Chikanma Edward, published by UIKTEN. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License. (CC BY-NC-ND 4.0)

Citation Information: SAR Journal. Volume 2, Issue 4, Pages 158-166, ISSN 2619-9955, DOI: 10.18421/SAR24-03, December 2019.

Received: 19 November 2019.
Revised:   07 December 2019.
Accepted: 14 December 2019.
Published: 30 December 2019.

Abstract:

In this study, fifty Kunun-zaki beverages were examined for the presence of extended spectrum beta lactamase (ESBL) and carbapenemase producing Escherichia coli. 20% of the samples were found to be contaminated with E. coli, whose counts ranged from 7.00×102-1.72×104(cfu/ml). All isolates were subjected to in-vitro antibiotics susceptibility testing which revealed complete sensitivity of the isolates to ofloxacin and total resistance to the carbapenems. 8 isolates showed multi-drug resistance, out of which, 4 were confirmed to be ESBL and carbapenemase producers. Such contaminated beverages if not regulated, can serve as a means for the dissemination of multi-drug resistant E. coli.

Keywords – Kunun-zaki, Escherichia coli, Extended-spectrum beta lactamase, carbapenemase, Umuahia.

                   

                                                                        Full text PDF